Synthesis of 3-Aryl-2, 3- Dihydrobenzofurans Analogues

Abstract

Abstract: Dihydrobenzofurans Analogues widely distributed in nature and have high application value. Among them, dihydrobenzofuran compounds are the key intermediates of drug synthesis, and they have the function of inhibiting tumor angiogenesis. Therefore, it is necessary to explore the synthesis method of dihydro-benzofuran compounds. The synthesis of 3-aryl-dihydro-benzo-furan(4) by the experimental scheme described in this chapter is expected to lead to the synthesis of a series of other 3-aryl- 2, 3-dihydrobenzofuran compounds, and then screening the target molecules with strong antitumor angiogenic activity.

Key words: Dihydrobenzofuran, intermediates, Antitumor angiogenesis activity, Synthesis

CLC Number:

O621.3

Lv Zeliang. Synthesis of 3-Aryl-2, 3- Dihydrobenzofurans Analogues[J]. JOURNAL OF QUJING NORMAL UNIVERSITY, 2016, 35(6): 28-36.

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