Research Progress on Pharmacological  activities of different extracts of  Medicinal Plants of Euonymus genera

Abstract

Abstract: The Euonymus genera has been widely used as medicinal plants in China as it mainly exhibits anti-inflammatory, promoting blood circulation, hemostatic, anti-diabetic, stabilizing blood lipids level, anti-tumor and other pharmacological properties. In this paper, we discussed about the pharmacological activities of different extracts from these medicinal plants and analyzed the differences and material basis between water-extracts and alcohol-extracts. It was found that the water-extracts mainly exhibited anti-diabetic, blood lipid regulation, coagulation and hemostatic effect while the alcohol-extracts mainly showed the activity of anti-tumor, anti- oxidation and anti-inflammation. The study can provides theoretical basis for further research on phytochemistry, pharmacology and clinical application of these medicinal plants.

Key words: Euonymus genera, water-extracts, ethanol-extracts, biological activity, extraction method

CLC Number:

R962

Duan Kunyuan, Zhang Huiying. Research Progress on Pharmacological activities of different extracts of Medicinal Plants of Euonymus genera[J]. JOURNAL OF QUJING NORMAL UNIVERSITY, 2019, 38(3): 19-23.

References

[1] 林士杰,刘原樟,徐加顺. 卫矛属种质资源开发利用研究概述[J].吉林林业科技,2009(2):17-19.
[2] 中国科学院中国植物志委员会. 中国植物志:第四十五卷第三分册[M].北京:科学出版社, 1999:123.
[3] 姚祖培, 陈建新, 李福如. 鬼箭羽化学、药理及临床应用概况[J]. 中国中医药信息杂志, 2000, 7(12):31-33.
[4] 朱红梅, 钟鸣. 扶芳藤及其提取物的有关药理作用的实验研究[J]. 中国中医药科技, 2000(3):170-174.
[5] 王巍, 王晋桦. 鸡血藤,鬼箭羽和土鳖虫调脂作用的比较[J]. 中国中药杂志, 1991, 16(5):299-301.
[6] 尚文斌, 程海波, 唐含艳. 鬼箭羽对糖尿病小鼠血糖及全血粘度的影响[J]. 南京中医药大学学报, 2000, 16(3):166-167.
[7] 夏卫军, 程海波, 张莉. 鬼箭羽治疗2型糖尿病实验研究[J]. 陕西中医, 2001, 22(8):505-507.
[8] 赵蒙蒙, 谢梦洲, 李路丹,等. 鬼箭羽对2型糖尿病大鼠胰岛β细胞形态学的影响[J]. 湖南中医药大学学报, 2010, 30(3):14-16.
[9] 孙学斌, 程明, 李娜,等. 卫矛不同有效部位总黄酮含量及抗氧化性的研究[J]. 植物研究, 2007, 27(5):619-621.
[10] 齐昉, 刘根尚, 佘靖,等. 鬼箭羽对实验性糖尿病小鼠血糖及血脂的影响[J]. 中国中医药信息杂志, 1998, 5(7):19-20.
[11] 吴玉强.常春卫矛及爬行卫矛提取物止血消瘀药效研究[J]. 中国实验方剂学杂志, 2011, 17(12):132-136.
[12] 朱智德, 罗宇东, 蒋林, 等. 瑶药扶芳藤对血管内皮细胞缺氧损伤的保护作用[J]. 中国医药导报, 2017, 14(10):26-30.
[13] 农毅清,蒋林,罗宇东,等.常春卫矛提取物对H2O2诱导的血管内皮细胞损伤的保护作用[J]. 中国药师, 2017, 20(5):805-808.
[14] 孙荣花, 周元飞, 邵莹,等. 桃叶卫矛叶提取物的体外抗氧化活性及对CCL_4致小鼠急性肝损伤的保护作用[J]. 辽宁中医药大学学报, 2015(11):28-31.
[15] Byung-Yoon C , Chan-Jo P, Dong-Gyu L , et al. Inhibitory effect of methanol extract of Euonymus alatus on matrix metalloproteinase-9[J]. Journal of Ethnopharmacology, 2003, 85(1):163-167.
[16] Seo U K , Lee Y J , Kim J K , et al. Large-scale and effective screening of Korean medicinal plants for inhibitory activity on matrix metalloproteinase-9[J]. Journal of Ethnopharmacology, 2005, 97(1):101-106.
[17] 方振峰.中药鬼箭羽的化学成分及抗肿瘤活性研究[D]. 沈阳:沈阳药科大学, 2007.
[18] 方振峰, 李占林, 王宇, 等. 鬼箭羽的化学成分研究[J]. 中草药, 2015, 38(13):810-812.
[19] Chung T W. Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism[J]. The Faseb Journal, 2004, 18(14):1670-1681.
[20]毛士龙.宝兴卫矛和山海螺化学成分及活性研究[D].上海:中国科学院上海药物研究所,1999.
[21] 吴建国, 曾凡波, 杨敬. 绿舒筋生物总碱的体外抗乳腺癌细胞株效应[J]. 华中科技大学学报(医学版), 2003, 32(6):665-666.
[22] Kitanaka S , Takido M , Mizoue K , et al. Cytotoxic Cardenolides from Woods of Euonymus alata.[J]. Chemical & Pharmaceutical Bulletin, 1996, 44(3):615-617.
[23]Li F , Ma J , Li C J , et al. Bioactive isopimarane diterpenoids from the stems of Euonymus oblongifolius[J]. Phytochemistry, 2017, 135(Complete):144-150.
[24] 谷树珍. 鬼箭羽醇提物的抑菌、抗炎作用研究[J]. 湖北民族学院学报(医学版), 2006, 23(1):17-19.
[25] 罗宇东, 张强, 蒋林等.常春卫矛提取物体外及体内抑菌作用的试验研究[J]. 中国当代医药, 2014(18):9-11.
[26]Zhou J , Wei X H , Zhang D M , et al. Anti-inflammatory pentacyclic triterpenes from the stems of Euonymus carnosus.[J]. Fitoterapia, 2017, 118:21-26.
[27] Yang Y L, Yang X Y, Guo Y Q. Bioactive terpenoids from Euonymus verrucosus var. pauciβorus showing NO inhibitory activities. [J]. Bioorganic Chemistry, 2019, 87:447–456.
[28] Park S H , Ko S K , Chung S H . Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice. [J]. Journal of Ethnopharmacology, 2005, 102(3):326-335.
[29] Van B N , San-Lang W , Thi N , et al. Novel Potent Hypoglycemic Compounds from Euonymus laxiflorus Champ. and Their Effect on Reducing Plasma Glucose in an ICR Mouse Model[J]. Molecules, 2018, 23(8):1928.
[30] Wan X, Huang H C,Wang X P,et al. Euonymus alatus and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways. [J]. Am J Transl Res,2019,11(1):106-119.

Research Progress on Pharmacological activities of different extracts of Medicinal Plants of Euonymus genera

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 0

Recommended Articles

Metrics

Comments