曲靖师范学院学报 ›› 2019, Vol. 38 ›› Issue (3): 19-23.

• 化学与生物学研究 • 上一篇    下一篇

卫矛属药用植物不同提取部位药理活性研究进展

段坤元, 张慧颖   

  1. 曲靖医学高等专科学校 药学系,云南 曲靖 655011
  • 收稿日期:2019-04-02 出版日期:2019-05-26
  • 通讯作者: 张慧颖,曲靖医学高等专科学校药学系副教授,主要从事天然药物化学、中药学研究.
  • 作者简介:段坤元,曲靖医学高等专科学校药学系助教,主要从事药物化学应用研究.
  • 基金资助:
    云南省教育厅科学研究基金项目“大理卫矛降血糖活性研究”(2016ZDX201).

Research Progress on Pharmacological activities of different extracts of Medicinal Plants of Euonymus genera

Duan Kunyuan, Zhang Huiying   

  1. Department of pharmacy,Qujing Medical College,Qujing Yunnan 655011,China
  • Received:2019-04-02 Published:2019-05-26

摘要: 卫矛属药用植物由于其在抗炎、活血止血、调节血糖血脂以及抗肿瘤方面具有突出活性而被广泛使用.研究了卫矛属药用植物因不同提取部位所表现出的生物活性差异特性,并着重分析了水提液部位和醇提液部位所产生的活性差别及其物质基础.研究发现水提液主要表现为降血糖血脂、凝血、止血等作用;而醇提部位主要表现出抗肿瘤、抗氧化、抗炎等活性作用.为该属植物的植物化学、药理学及其进一步的临床应用提供参考依据.

关键词: 卫矛属, 水提液, 醇提液, 生物活性, 提取方法

Abstract: The Euonymus genera has been widely used as medicinal plants in China as it mainly exhibits anti-inflammatory, promoting blood circulation, hemostatic, anti-diabetic, stabilizing blood lipids level, anti-tumor and other pharmacological properties. In this paper, we discussed about the pharmacological activities of different extracts from these medicinal plants and analyzed the differences and material basis between water-extracts and alcohol-extracts. It was found that the water-extracts mainly exhibited anti-diabetic, blood lipid regulation, coagulation and hemostatic effect while the alcohol-extracts mainly showed the activity of anti-tumor, anti- oxidation and anti-inflammation. The study can provides theoretical basis for further research on phytochemistry, pharmacology and clinical application of these medicinal plants.

Key words: Euonymus genera, water-extracts, ethanol-extracts, biological activity, extraction method

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